EDITORIALS Overprescribing proton pump inhibitors Is expensive and not evidence based
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چکیده
http://bmj.com/cgi/content/full/336/7634/2 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/336/7634/2#BIBL This article cites 9 articles, 4 of which can be accessed free at: Rapid responses http://bmj.com/cgi/eletter-submit/336/7634/2 You can respond to this article at: http://bmj.com/cgi/content/full/336/7634/2#responses for free at: 17 rapid responses have been posted to this article, which you can access
منابع مشابه
Formulary Substitution of Proton Pump Inhibitors Based on Acquisition Price: Changes in Usage and Costs of Acid-Suppressant Therapies
0.72-fold in the ICU after the switch (95% CI, 0.52–1.00, P = .04). Conclusion. Substituting a less expensive PPI did not alter usage outside the ICU, but it was associated with increased usage in the ICU. Conversely, the use of IV H2RAs decreased in the ICU. Despite substantially more PPI use after the formulary switch, the cost of acid-suppressant therapy was unchanged overall; it was lower i...
متن کاملCONTINUING EDuCAtiON Review of the Clopidogrel - Proton Pump inhibitor interaction
OBjECTiVES 1. Describe the proposed mechanism of the interaction between clopidogrel and proton pump inhibitors. 2. Summarize the pharmacologic/pharmacodynamic evidence for the interaction between clopidogrel and proton pump inhibitors. 3. Summarize the clinical evidence for the interaction between clopidogrel and proton pump inhibitors. 4. Describe the food and Drug Administration’s updated wa...
متن کاملGeneral practice variation when initiating long-term prescribing of proton pump inhibitors: a nationwide cohort study
BACKGROUND Suggestions of overprescribing of proton pump inhibitors (PPIs) for long-term treatment in primary care have been raised. This study aims to analyse associations between general practice characteristics and initiating long-term treatment with PPIs. METHODS A nationwide register-based cohort study of patients over 18 years redeeming first-time prescription for PPI issued by a genera...
متن کاملOral Proton Pump Inhibitors
There is currently a lack of evidence to suggest superior clinical efficacy of one oral proton pump inhibitor over any other. Proton pump inhibitors display similar doseresponse relationships with similar potencies and efficacies at the equivalent dose. The decision to select one proton pump inhibitor over another is likely to be based on the agents’ licensed indication, patient tolerability an...
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INTRODUCTION Antiplatelet therapy remains one of the cornerstones in the management of non-cardioembolic ischemic stroke. However, a significant percentage of patients have concomitant gastroesophageal reflux or peptic ulcer disease that requires acid-reducing medications, the most powerful and effective being the proton pump inhibitors (PPIs). Antiplatelet efficacy, at least in vivo, and parti...
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